中文簡介

《毒理學(xué)研究》旨在發(fā)布卓越和創(chuàng)新的前沿研究，推動毒理學(xué)并具有國際影響力。文章應(yīng)涵蓋毒性反應(yīng)的化學(xué)或生物方面以及所涉及的機制。該期刊的范圍包括以下內(nèi)容：納米毒理學(xué)，強烈鼓勵研究納米材料和與人類健康直接相關(guān)的常見納米材料的毒性反應(yīng)的生化或分子機制。致癌性，包括致癌物的作用方式，遺傳毒性和突變的研究毒性的生物標(biāo)志物，包括對其鑒定，驗證和利用的研究計算和預(yù)測毒理學(xué)，包括體外，體內(nèi)和計算機毒性研究以及預(yù)測工具和模型的開發(fā)。鼓勵考慮采用替代方法進行體內(nèi)研究。系統(tǒng)毒理學(xué)，描述化學(xué)物質(zhì)對特定器官或系統(tǒng)（例如，免疫，神經(jīng)，生殖，呼吸）的毒理學(xué)影響的研究，包括納入基因組學(xué)，代謝組學(xué)和蛋白質(zhì)組學(xué)數(shù)據(jù)的研究風(fēng)險評估，提供毒理學(xué)數(shù)據(jù)或信息的研究 - 例如危害識別，劑量反應(yīng)評估風(fēng)險評估或監(jiān)管制定的風(fēng)險暴露評估環(huán)境毒理學(xué)，如果對人類健康有更廣泛的益處，鼓勵報告生態(tài)系統(tǒng)內(nèi)生物的毒理學(xué)數(shù)據(jù)。臨床毒理學(xué)，有關(guān)毒理學(xué)研究的臨床試驗或藥物應(yīng)用的研究，包括轉(zhuǎn)化毒理學(xué)，研究將臨床應(yīng)用的毒性反應(yīng)的分子理解轉(zhuǎn)化為臨床應(yīng)用。食品毒理學(xué)，與食品和營養(yǎng)有關(guān)的化學(xué)提取物的毒理學(xué)研究。涉及無特征提取物或其中食物僅具有有限或當(dāng)?shù)乩娴难芯繎?yīng)在其他地方提交。分析計量學(xué)，包括新分析方法和應(yīng)用的研究

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英文簡介

Toxicology Research aims to publish cutting edge research that is excellent and innovative, that drives toxicology and has international impact. Articles should cover chemical or biological aspects of the toxic response and the mechanisms involved.The journal''s scope includes the following.Nanotoxicology, studies on the biochemical or molecular mechanisms of toxic responses to nanomaterials and common nanomaterials which are of direct relevance to human health, are strongly encouraged. Carcinogenicity, including studies on mode of action of carcinogens, genotoxicity and mutationBiomarkers of toxicity, including studies on their identification, validation, and utilisationComputational and predictive toxicology, including in vitro, in vivo and in silico studies of toxicity and the development of predictive tools and models. Work considering alternative methods to in vivo studies is encouraged.Systems toxicology, studies that describe the toxicological effects of chemicals on specific organs or systems (for example, immune, nervous, reproductive, respiratory), including studies that incorporate genomic, metabonomic and proteomic dataRisk assessment, studies which provide toxicological data or information – such as hazard identification, dose-response assessmentExposure assessment for the development of risk assessments or regulationEnvironmental toxicology, studies reporting toxicology data for organisms within an ecosystem are encouraged if there is a wider benefit to human health.Clinical toxicology, studies relating to clinical trials or medicinal applications of toxicological research, including translational toxicology, Studies translating a molecular understanding of the toxic response to clinical application.Food toxicology, toxicological studies of chemical extracts related to food and nutrition. Studies that involve uncharacterised extracts or in which the food substance is only of limited or local interest should be submitted elsewhere.Analytical metrology, including studies of new analytical methods and applications