中文簡介

近年來，先進的分子研究技術(shù)已經(jīng)改變了血液學。隨著對血液病認識的提高，我們現(xiàn)在有機會研究和評估新的生物療法、新藥和藥物組合、新的治療計劃和包括干細胞移植在內(nèi)的新方法。我們還可以期待蛋白質(zhì)組學、分子遺傳學和生物標志物的研究能夠促進新的診斷方法和合適的治療方法的識別。隨著我們對血細胞和造血組織的形成和功能的認識的進一步提高，對血液學家來說，采用這些新范式并制定綜合策略來確定可能的最佳患者護理將是一個重大挑戰(zhàn)?！堆簩W專家評論》(1747-4086)將這些進展納入背景，并探討如何將其直接轉(zhuǎn)化為臨床實踐。領(lǐng)域包括:?急性白血病?貧血?出血失調(diào)?骨髓和造血干細胞移植?細胞疾病?慢性白血病?鐵代謝紊亂?霍吉金斯疾病?血液學感染?免疫缺陷綜合癥?自身免疫性疾病?骨髓衰竭綜合征?多發(fā)性骨髓瘤和淀粉樣變性?嗜中性白血球減少癥?非霍奇金淋巴瘤?兒科血液學?血小板疾病?血栓形成和止血?輸血醫(yī)學《血液學專家評論》提供評論和分析，闡明血液學的最佳臨床實踐，并將免疫學、干細胞研究、細胞和基因治療等領(lǐng)域的研究進展轉(zhuǎn)化為臨床應(yīng)用。

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英文簡介

Advanced molecular research techniques have transformed hematology in recent years. With improved understanding of hematologic diseases, we now have the opportunity to research and evaluate new biological therapies, new drugs and drug combinations, new treatment schedules and novel approaches including stem cell transplantation. We can also expect proteomics, molecular genetics and biomarker research to facilitate new diagnostic approaches and the identification of appropriate therapies. Further advances in our knowledge regarding the formation and function of blood cells and blood-forming tissues should ensue, and it will be a major challenge for hematologists to adopt these new paradigms and develop integrated strategies to define the best possible patient care. Expert Review of Hematology (1747-4086) puts these advances in context and explores how they will translate directly into clinical practice. Areas covered include:? Acute leukemias ? Anemias ? Bleeding disorders ? Bone marrow and hematopoietic stem cell transplantation ? Cellular disorders ? Chronic leukemias ? Disorders of iron metabolism ? Hodgkins disease ? Infection in hematology ? Immunodeficiency syndromes ? Autoimmune diseases ? Marrow failure syndromes ? Multiple myeloma and amyloidosis ? Neutropenia ? Non-Hodgkin lymphomas ? Pediatric hematology ? Platelet disorders ? Thrombosis and hemostasis ? Transfusion medicine Expert Review of Hematology provides commentary and analysis to elucidate best clinical practice in hematology and to translate advances in research – in areas such as immunology, stem cell research, and cell and gene therapy – into the clinical context.