中文簡(jiǎn)介

近年來(lái)，先進(jìn)的分子研究技術(shù)已經(jīng)改變了血液學(xué)。隨著對(duì)血液病認(rèn)識(shí)的提高，我們現(xiàn)在有機(jī)會(huì)研究和評(píng)估新的生物療法、新藥和藥物組合、新的治療計(jì)劃和包括干細(xì)胞移植在內(nèi)的新方法。我們還可以期待蛋白質(zhì)組學(xué)、分子遺傳學(xué)和生物標(biāo)志物的研究能夠促進(jìn)新的診斷方法和合適的治療方法的識(shí)別。隨著我們對(duì)血細(xì)胞和造血組織的形成和功能的認(rèn)識(shí)的進(jìn)一步提高，對(duì)血液學(xué)家來(lái)說(shuō)，采用這些新范式并制定綜合策略來(lái)確定可能的最佳患者護(hù)理將是一個(gè)重大挑戰(zhàn)?！堆簩W(xué)專(zhuān)家評(píng)論》(1747-4086)將這些進(jìn)展納入背景，并探討如何將其直接轉(zhuǎn)化為臨床實(shí)踐。領(lǐng)域包括:?急性白血病?貧血?出血失調(diào)?骨髓和造血干細(xì)胞移植?細(xì)胞疾病?慢性白血病?鐵代謝紊亂?霍吉金斯疾病?血液學(xué)感染?免疫缺陷綜合癥?自身免疫性疾病?骨髓衰竭綜合征?多發(fā)性骨髓瘤和淀粉樣變性?嗜中性白血球減少癥?非霍奇金淋巴瘤?兒科血液學(xué)?血小板疾病?血栓形成和止血?輸血醫(yī)學(xué)《血液學(xué)專(zhuān)家評(píng)論》提供評(píng)論和分析，闡明血液學(xué)的最佳臨床實(shí)踐，并將免疫學(xué)、干細(xì)胞研究、細(xì)胞和基因治療等領(lǐng)域的研究進(jìn)展轉(zhuǎn)化為臨床應(yīng)用。

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英文簡(jiǎn)介

Advanced molecular research techniques have transformed hematology in recent years. With improved understanding of hematologic diseases, we now have the opportunity to research and evaluate new biological therapies, new drugs and drug combinations, new treatment schedules and novel approaches including stem cell transplantation. We can also expect proteomics, molecular genetics and biomarker research to facilitate new diagnostic approaches and the identification of appropriate therapies. Further advances in our knowledge regarding the formation and function of blood cells and blood-forming tissues should ensue, and it will be a major challenge for hematologists to adopt these new paradigms and develop integrated strategies to define the best possible patient care. Expert Review of Hematology (1747-4086) puts these advances in context and explores how they will translate directly into clinical practice. Areas covered include:? Acute leukemias ? Anemias ? Bleeding disorders ? Bone marrow and hematopoietic stem cell transplantation ? Cellular disorders ? Chronic leukemias ? Disorders of iron metabolism ? Hodgkins disease ? Infection in hematology ? Immunodeficiency syndromes ? Autoimmune diseases ? Marrow failure syndromes ? Multiple myeloma and amyloidosis ? Neutropenia ? Non-Hodgkin lymphomas ? Pediatric hematology ? Platelet disorders ? Thrombosis and hemostasis ? Transfusion medicine Expert Review of Hematology provides commentary and analysis to elucidate best clinical practice in hematology and to translate advances in research – in areas such as immunology, stem cell research, and cell and gene therapy – into the clinical context.