中文簡介

體外毒理學將發(fā)表原始的研究論文和偶爾的評論，使用體外技術來確定化學品的毒性作用和闡明其作用機制。該雜志將鼓勵提交研究報告，通過利用細胞或組織培養(yǎng)、灌注器官、組織切片、分離細胞或亞細胞組分（包括酶和細胞受體），研究體內遇到的毒性作用機制，或更好地描述體外和體內觀察到的毒性作用之間的關系。離子。毒理學的各個方面都將涵蓋，包括特定器官毒性（如神經毒性、腎毒性）、各種毒性現(xiàn)象（如致癌或致畸），以及毒性評估和研究的新體外模型的開發(fā)、表征和驗證。期刊的編輯政策將牢牢扎根于對高質量科學的需求，以支持健康或安全決策，并將重點放在有助于評估化學品對人類和動物的危害的結果上。新成員現(xiàn)在可以享受特殊費率。欲了解更多信息，請聯(lián)系Diane Benford博士，英國吉爾福德薩里大學羅本斯提夫研究所秘書；電話：+441483259204；傳真：+441483503517；電子郵件：d.benford@surrey.ac.uk或訪問http://leden.tref.nl/ruttend/網(wǎng)站

投稿網(wǎng)址：http://ees.elsevier.com/tiv/

英文簡介

Toxicology in Vitro will publish original research papers and occasional reviews on the use of in vitro techniques for determining the toxic effects of chemicals and elucidating their mechanisms of action. The Journal will encourage the submission of studies which, by utilising cell or tissue culture, perfused organs, tissue slices, isolated cells or subcellular fractions, including enzymes and cell-receptors, investigate the mechanisms of toxic effects encountered in vivo or better characterize the relationship between in vitro and in vivo observations. All aspects of toxicology will be covered, including specific organ toxicity (eg neurotoxicity, nephrotoxicity), various toxic phenomena such as carcinogenesis or teratogenesis, and the development, characterization and validation of new in vitro models for the assessment and study of toxicity. The Journal's editorial policy will be firmly rooted in the need for high-quality science in support of health or safety decisions, and emphasis will be placed on results that facilitate evaluation of the hazard of chemicals to man and animals. NEW! Special rate for ESTIV members now available. For more information contact Dr. Diane Benford, ESTIV Secretary, Robens Institute, University of Surrey, Guildford, Surrey, GU2 5XH, U.K.; Tel: +44 1483 259 204; Fax: +44 1483 503 517; E-mail: d.benford@surrey.ac.uk or visit the ESTIV website at http://leden.tref.nl/ruttend/