中文簡(jiǎn)介

體外毒理學(xué)將發(fā)表原始的研究論文和偶爾的評(píng)論，使用體外技術(shù)來確定化學(xué)品的毒性作用和闡明其作用機(jī)制。該雜志將鼓勵(lì)提交研究報(bào)告，通過利用細(xì)胞或組織培養(yǎng)、灌注器官、組織切片、分離細(xì)胞或亞細(xì)胞組分（包括酶和細(xì)胞受體），研究體內(nèi)遇到的毒性作用機(jī)制，或更好地描述體外和體內(nèi)觀察到的毒性作用之間的關(guān)系。離子。毒理學(xué)的各個(gè)方面都將涵蓋，包括特定器官毒性（如神經(jīng)毒性、腎毒性）、各種毒性現(xiàn)象（如致癌或致畸），以及毒性評(píng)估和研究的新體外模型的開發(fā)、表征和驗(yàn)證。期刊的編輯政策將牢牢扎根于對(duì)高質(zhì)量科學(xué)的需求，以支持健康或安全決策，并將重點(diǎn)放在有助于評(píng)估化學(xué)品對(duì)人類和動(dòng)物的危害的結(jié)果上。新成員現(xiàn)在可以享受特殊費(fèi)率。欲了解更多信息，請(qǐng)聯(lián)系Diane Benford博士，英國吉爾福德薩里大學(xué)羅本斯提夫研究所秘書；電話：+441483259204；傳真：+441483503517；電子郵件：d.benford@surrey.ac.uk或訪問http://leden.tref.nl/ruttend/網(wǎng)站

投稿網(wǎng)址：http://ees.elsevier.com/tiv/

英文簡(jiǎn)介

Toxicology in Vitro will publish original research papers and occasional reviews on the use of in vitro techniques for determining the toxic effects of chemicals and elucidating their mechanisms of action. The Journal will encourage the submission of studies which, by utilising cell or tissue culture, perfused organs, tissue slices, isolated cells or subcellular fractions, including enzymes and cell-receptors, investigate the mechanisms of toxic effects encountered in vivo or better characterize the relationship between in vitro and in vivo observations. All aspects of toxicology will be covered, including specific organ toxicity (eg neurotoxicity, nephrotoxicity), various toxic phenomena such as carcinogenesis or teratogenesis, and the development, characterization and validation of new in vitro models for the assessment and study of toxicity. The Journal's editorial policy will be firmly rooted in the need for high-quality science in support of health or safety decisions, and emphasis will be placed on results that facilitate evaluation of the hazard of chemicals to man and animals. NEW! Special rate for ESTIV members now available. For more information contact Dr. Diane Benford, ESTIV Secretary, Robens Institute, University of Surrey, Guildford, Surrey, GU2 5XH, U.K.; Tel: +44 1483 259 204; Fax: +44 1483 503 517; E-mail: d.benford@surrey.ac.uk or visit the ESTIV website at http://leden.tref.nl/ruttend/