中文簡介

逆轉(zhuǎn)錄病毒是一個(gè)開放的訪問，在線期刊，發(fā)布嚴(yán)格的同行評審，高影響的文章的基本逆轉(zhuǎn)錄病毒研究。逆轉(zhuǎn)錄病毒是在動(dòng)物身上發(fā)現(xiàn)的。描述良好的例子包括鳥類，小鼠和靈長類動(dòng)物逆轉(zhuǎn)錄病毒。兩種人類逆轉(zhuǎn)錄病毒是特別重要的病原體。這些是人體免疫缺陷病毒，hiv，和人類t細(xì)胞白血病病毒。hiv導(dǎo)致艾滋病，而htlv-i是成人t細(xì)胞白血病的病因。目前有大量關(guān)于hiv和htlv-i的基礎(chǔ)研究，涉及基因表達(dá)、病毒結(jié)構(gòu)-組裝、整合、復(fù)制和發(fā)病機(jī)制。逆轉(zhuǎn)錄病毒的研究包括人類和動(dòng)物逆轉(zhuǎn)錄病毒的研究。在任何一期現(xiàn)存的印刷病毒學(xué)雜志上，關(guān)于逆轉(zhuǎn)錄病毒，特別是靈長類動(dòng)物逆轉(zhuǎn)錄病毒的研究論文，構(gòu)成了最大的手稿亞類。逆轉(zhuǎn)錄病毒對包括免疫缺陷和癌癥在內(nèi)的多種重要疾病負(fù)責(zé)。因此，開放存取期刊有很大的出版需求和研究興趣，它強(qiáng)調(diào)基本的逆轉(zhuǎn)錄病毒研究。這種開放訪問格式非常適合快速向廣大受眾傳遞尖端信息。

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英文簡介

Retrovirology is an Open Access, online journal that publishes stringently peer-reviewed, high-impact articles on basic retrovirus research. Retroviruses are pleiotropically found in animals. Well-described examples include avian, murine and primate retroviruses. Two human retroviruses are especially important pathogens. These are the human immunodeficiency virus, HIV, and the human T-cell leukemia virus, HTLV. HIV causes AIDS while HTLV-I is the etiological agent for adult T-cell leukemia. There is a large amount of basic research being conducted on HIV and HTLV-I spanning gene expression, virus structure-assembly, integration, replication, and pathogenesis. Retrovirology intends to cover these areas of human and animal retrovirus research. In any given issue of an extant print virology journal, research papers on retroviruses, especially primate retroviruses, make up the largest subcategory of manuscripts. Retroviruses are responsible for many kinds of medically important pathologies including immunodeficiencies and cancers. Hence, there is a large publication demand and a significant research interest for an Open Access journal, which emphasizes basic retrovirus research. The Open Access format is ideally suited for communicating cutting edge information to a large audience quickly.