中文簡(jiǎn)介

該雜志為寄生蟲原生動(dòng)物和蠕蟲的分子生物學(xué)和生物化學(xué)研究及其與最終宿主和中間宿主的相互作用的快速出版提供了一個(gè)媒介。所涵蓋的主要范疇包括:?DNA、RNA、蛋白質(zhì)、脂類、碳水化合物和小分子量物質(zhì)的結(jié)構(gòu)、生物合成、降解、性質(zhì)和功能?中間代謝和生物能學(xué)?藥物靶點(diǎn)表征及抗寄生蟲藥物的作用模式?膜結(jié)構(gòu)和功能的分子和生化方面?寄主-寄主關(guān)系，主要關(guān)注寄主，特別是與特定的寄主分子相關(guān)的寄主-寄主關(guān)系。?基因和基因組結(jié)構(gòu)、功能和表達(dá)分析?分析寄生蟲種群中與基因交換、發(fā)病機(jī)制、藥物和疫苗靶點(diǎn)表征以及耐藥性相關(guān)的變異。?寄生蟲蛋白的轉(zhuǎn)運(yùn)、細(xì)胞器的生物發(fā)生和細(xì)胞結(jié)構(gòu)，特別是特定分子的作用?寄生蟲在分子水平上對(duì)細(xì)胞的死亡、發(fā)育和分裂進(jìn)行程序化處理只有當(dāng)論文屬于這些領(lǐng)域，如果它們包含有高科學(xué)質(zhì)量的原創(chuàng)和完整的作品，并且呈現(xiàn)得很好，才會(huì)被接受發(fā)表。僅證實(shí)以前在其他生物體中研究過的基因的保守功能的論文將不予考慮。此外，以下工作領(lǐng)域更適合于其他期刊:?主要關(guān)注宿主反應(yīng)的研究(如免疫學(xué))?調(diào)查報(bào)告等位基因或應(yīng)變頻率在不同地區(qū)?在沒有生物實(shí)驗(yàn)的硅模型或計(jì)算工作中?報(bào)告與生物學(xué)無關(guān)的等位基因或菌株頻率的調(diào)查(例如，耐藥性或發(fā)病機(jī)制)

投稿網(wǎng)址：http://ees.elsevier.com/molbio/

英文簡(jiǎn)介

The journal provides a medium for rapid publication of investigations of the molecular biology and biochemistry of parasitic protozoa and helminths and their interactions with both the definitive and intermediate host. The main subject areas covered are:? the structure, biosynthesis, degradation, properties and function of DNA, RNA, proteins, lipids, carbohydrates and small molecular-weight substances? intermediary metabolism and bioenergetics? drug target characterization and the mode of action of antiparasitic drugs? molecular and biochemical aspects of membrane structure and function? host-parasite relationships that focus on the parasite, particularly as related to specific parasite molecules.? analysis of genes and genome structure, function and expression? analysis of variation in parasite populations relevant to genetic exchange, pathogenesis, drug and vaccine target characterization, and drug resistance.? parasite protein trafficking, organelle biogenesis, and cellular structure especially with reference to the roles of specific molecules? parasite programmed cell death, development, and cell division at the molecular levelPapers will only be accepted for publication if they fall within these areas, if they contain original and complete work of high scientific quality, and if they are well presented. Papers solely confirming the conserved functions of genes previously studied in other organisms will not be considered.Additionally the following areas of work are better suited to other journals:? studies predominantly focused on the host response (e.g. immunology) ? surveys reporting allele or strain frequencies in various regions ? in silico modeling or computational work without biological experiments ? surveys reporting allele or strain frequencies not linked to biological relevance (e.g., drug resistance, or pathogenesis)