中文簡(jiǎn)介

AJHG提供了關(guān)于人類遺傳、遺傳原理在醫(yī)學(xué)和公共政策中的應(yīng)用以及分子和細(xì)胞生物學(xué)相關(guān)領(lǐng)域的研究和綜述的記錄。AJHG探索的主題包括行為遺傳學(xué)、生物化學(xué)遺傳學(xué)、臨床遺傳學(xué)、細(xì)胞遺傳學(xué)、畸形學(xué)、基因治療、遺傳咨詢、遺傳流行病學(xué)、基因組學(xué)、免疫遺傳學(xué)、分子遺傳學(xué)、神經(jīng)遺傳學(xué)和群體遺傳學(xué)。AJHG歡迎提交關(guān)于人類遺傳學(xué)各方面及時(shí)主題的文章和報(bào)告，包括與人類遺傳學(xué)直接相關(guān)的模型生物體的研究。手稿應(yīng)該以一種讓代表人類遺傳學(xué)不同背景的研究人員能夠理解的方式來寫。歡迎介紹遺傳學(xué)界普遍感興趣的新統(tǒng)計(jì)方法。新方法應(yīng)該與現(xiàn)有方法進(jìn)行比較，使用真實(shí)數(shù)據(jù)和/或基于真實(shí)數(shù)據(jù)示例的參數(shù)(例如，單倍型頻率、效果大小)進(jìn)行模擬(例如，來自HapMap項(xiàng)目的標(biāo)記或單倍型數(shù)據(jù))。所有小說的計(jì)算機(jī)程序必須在手稿出版前公開，并且手稿的Web資源部分必須包含網(wǎng)站的URL。也歡迎來信評(píng)論以前在AJHG上發(fā)表的材料。AJHG不發(fā)表關(guān)于單個(gè)突變的報(bào)告，也不發(fā)表對(duì)先前確定基因座的突變調(diào)查報(bào)告，除非它們具有不尋常的意義和實(shí)質(zhì)性的見解。只有在特別感興趣的情況下，才會(huì)考慮對(duì)新鏈接分配的說明。負(fù)面數(shù)據(jù)的報(bào)告通常不予考慮。

英文簡(jiǎn)介

AJHG provides a record of research and review relating to heredity in humans and to the application of genetic principles in medicine and public policy, as well as in related areas of molecular and cell biology. Topics explored by AJHG include behavioral genetics, biochemical genetics, clinical genetics, cytogenetics, dysmorphology, gene therapy, genetic counseling, genetic epidemiology, genomics, immunogenetics, molecular genetics, neurogenetics, and population genetics.AJHG welcomes submissions of articles and reports on timely subjects concerning all aspects of human genetics, including studies of model organisms that are of direct relevance to human genetics. Manuscripts should be written in a manner accessible to investigators representing diverse backgrounds in human genetics. Descriptions of new statistical methods of general interest to the genetics community are welcome. New methods should be compared to existing methods with the use of real data and/or simulations with parameters (e.g., haplotype frequencies, effect sizes) that are based on a real data example (e.g., marker or haplotype data from the HapMap project). All novel computer programs must be made publicly available by the time that the manuscript is published, and a URL for the website must be included in the Web Resources section of the manuscript. Letters commenting on material previously published in AJHG are also welcome.AJHG does not publish reports of either single mutations or mutational surveys of previously identified loci unless they have unusual significance and substantial insight. Descriptions of new linkage assignments will be considered only if they are of special interest. Reports of negative data will not normally be considered.