中文簡介

由愛思唯爾科學(xué)出版。ISSN: 1567 - 5769。國際免疫藥理學(xué)和免疫藥理學(xué)雜志的合并。國際免疫藥理學(xué)是發(fā)表有關(guān)免疫學(xué)、藥理學(xué)、細(xì)胞因子生物學(xué)、免疫治療、免疫病理學(xué)和免疫毒理學(xué)交叉領(lǐng)域的原始研究論文的主要工具。也歡迎評論包含這些主題的文章。適宜提交的研究材料包括:采用任何類型免疫治療的臨床研究，包括使用:細(xì)菌和化學(xué)制劑;胸腺激素、干擾素、淋巴因子等，用于移植和癌癥、免疫缺陷、慢性感染和過敏、炎癥或自身免疫性疾病等。研究這些藥物對特定免疫功能參數(shù)的作用機(jī)制以及整體臨床狀態(tài)。臨床前動物研究和體外研究免疫增強(qiáng)劑、免疫調(diào)節(jié)劑、免疫佐劑和其他藥物對參與免疫或過敏反應(yīng)的細(xì)胞的作用機(jī)制。影響淋巴系統(tǒng)的藥理化合物、微生物制品和毒理學(xué)制劑及其作用機(jī)制。在免疫反應(yīng)中激活基因或改變轉(zhuǎn)錄和翻譯的物質(zhì)。通過具有藥理活性的免疫或相關(guān)途徑激活、產(chǎn)生或釋放的物質(zhì)。細(xì)胞因子及其受體的產(chǎn)生、功能和調(diào)控。經(jīng)典藥理學(xué)研究在免疫反應(yīng)中釋放的趨化因子和生物活性因子的影響。免疫系統(tǒng)中淋巴細(xì)胞和其他細(xì)胞上藥物和激素受體的性質(zhì)和功能的研究。細(xì)胞源性或體液性因子的研究，這些因子修飾免疫系統(tǒng)，導(dǎo)致細(xì)胞毒性、誘導(dǎo)抗體產(chǎn)生和介導(dǎo)炎癥反應(yīng)。免疫學(xué)檢測方法的發(fā)展及其在疾病中的應(yīng)用，包括藥物、激素、環(huán)核苷酸、腫瘤抗原等的檢測。

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英文簡介

Published by Elsevier Science. ISSN: 1567-5769.Merger of International Journal of Immunopharmacology and Immunopharmacology. International Immunopharmacology is the primary vehicle for the publication of original research papers pertinent to the overlapping areas of immunology, pharmacology, cytokine biology, immunotherapy, immunopathology and immunotoxicology. Review articles that encompass these subjects are also welcome. The subject material appropriate for submission includes: Clinical studies employing immunotherapy of any type including the use of: bacterial and chemical agents; thymic hormones, interferon, lymphokines, etc., in transplantation and diseases such as cancer, immunodeficiency, chronic infection and allergic, inflammatory or autoimmune disorders. Studies on the mechanisms of action of these agents for specific parameters of immune competence as well as the overall clinical state. Pre-clinical animal studies and in vitro studies on mechanisms of action with immunopotentiators, immunomodulators, immunoadjuvants and other pharmacological agents active on cells participating in immune or allergic responses. Pharmacological compounds, microbial products and toxicological agents that affect the lymphoid system, and their mechanisms of action. Agents that activate genes or modify transcription and translation within the immune response. Substances activated, generated, or released through immunologic or related pathways that are pharmacologically active. Production, function and regulation of cytokines and their receptors. Classical pharmacological studies on the effects of chemokines and bioactive factors released during immunological reactions. Studies on the nature and function of drug and hormone receptors on lymphocytes and other cells in the immune system. Studies of cell-derived or humoral factors that modify the immune system causing cytotoxicity, inducing antibody production and mediating inflammatory responses. The development of immunologically based assays and their application to disease, including assays for drugs, hormones, cyclic nucleotides, tumor antigens, etc.