中文簡(jiǎn)介

藥物化學(xué)已迅速發(fā)展成為一個(gè)高度跨學(xué)科的領(lǐng)域，豐富了從化學(xué)信息學(xué)家和物理化學(xué)家到分子生物學(xué)家和藥理學(xué)家的廣泛專(zhuān)業(yè)領(lǐng)域的專(zhuān)家的合作努力。未來(lái)的藥物化學(xué)每月為這個(gè)不斷擴(kuò)大和多樣化的社區(qū)提供評(píng)論和辯論的機(jī)會(huì)。該雜志展示了藥物研發(fā)的里程碑和新興研究的專(zhuān)家分析——從目標(biāo)的識(shí)別，到生物活性藥物的發(fā)現(xiàn)、設(shè)計(jì)、合成和評(píng)估。沒(méi)有比這更大的壓力來(lái)更快、更有效地生產(chǎn)有效、安全的化合物。未來(lái)的藥物化學(xué)提供了一個(gè)論壇，為快速出版的原始研究和批評(píng)的最新里程碑在該領(lǐng)域。重點(diǎn)放在確保該期刊激發(fā)人們對(duì)預(yù)期將在影響藥物化學(xué)未來(lái)方向方面發(fā)揮越來(lái)越重要作用的問(wèn)題的認(rèn)識(shí)。在相關(guān)領(lǐng)域，還積極鼓勵(lì)在生物技術(shù)、酶學(xué)、綠色化學(xué)、基因組學(xué)、免疫學(xué)、材料科學(xué)、被忽視疾病和孤兒藥物、藥物基因組學(xué)、蛋白質(zhì)組學(xué)和毒理學(xué)等多方面作出貢獻(xiàn)。主要的主題包括：藥物發(fā)現(xiàn)技術(shù)；新型先導(dǎo)化合物的設(shè)計(jì)與合成；綜合和建模的計(jì)算方法；結(jié)構(gòu)表征的生物物理技術(shù)；綜述新的治療策略和新出現(xiàn)的靶點(diǎn)；藥物靶向與給藥；托克斯ADME /調(diào)查；對(duì)科學(xué)政策、經(jīng)濟(jì)和知識(shí)產(chǎn)權(quán)問(wèn)題的評(píng)論。除了核心內(nèi)容的審查，專(zhuān)利審查，觀點(diǎn)和原創(chuàng)研究，該雜志還提供開(kāi)明的評(píng)論和意見(jiàn)，對(duì)與學(xué)術(shù)界和工業(yè)界有關(guān)的辯論熱點(diǎn)領(lǐng)域，以及會(huì)議報(bào)告，采訪等。通過(guò)保持對(duì)新興主題的高度反應(yīng)，并提供深入的藥物興趣和治療方法的分析，該雜志將作為一個(gè)有價(jià)值的參考，不僅對(duì)藥物化學(xué)家，而且對(duì)所有對(duì)藥物科學(xué)的進(jìn)步感興趣的人。該雜志歡迎不請(qǐng)自來(lái)的文章建議。

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英文簡(jiǎn)介

Medicinal chemistry has evolved rapidly into a highly interdisciplinary field, enriched by the collaborative efforts of experts from a wide spectrum of specialist areas, from chemoinformaticians and physical chemists to molecular biologists and pharmacologists. Future Medicinal Chemistry provides a monthly point of access to commentary and debate for this ever-expanding and diversifying community. The journal showcases milestones in pharmaceutical R&D and features expert analysis of emerging research-from the identification of targets, through to the discovery, design, synthesis and evaluation of bioactive agents.There has never been more pressure to produce potent and safe compounds faster and more efficiently. Future Medicinal Chemistry offers a forum for the rapid publication of original research and critical reviews of the latest milestones in the field. Strong emphasis is placed on ensuring that the journal stimulates awareness of issues that are anticipated to play an increasingly central role in influencing the future direction of pharmaceutical chemistry. Where relevant, contributions are also actively encouraged on areas as diverse as biotechnology, enzymology, green chemistry, genomics, immunology, materials science, neglected diseases and orphan drugs, pharmacogenomics, proteomics and toxicology.Principal themes include:Drug discovery technologiesDesign and synthesis of novel lead compoundsComputational approaches to synthesis and modelingBiophysical techniques for structural characterizationOverviews of novel therapeutic strategies and emerging targetsDrug targeting and deliveryADME/Tox investigationsCommentary on science policy, economic and IP issuesIn addition to its core content of Reviews, Patent Reviews, Perspectives and Original Research, the journal also features enlightened commentary and opinion on topical areas of debate relevant to academia and industry, as well as conference reports, interviews and more.By remaining highly responsive to emerging themes, and providing in-depth analysis of agents of medicinal interest and therapeutic approaches, the journal will act as a valuable reference, not only for medicinal chemists, but for all those interested in the advancement of pharmaceutical science.The journal welcomes unsolicited article proposals.