中文簡介

該雜志發(fā)表了生物藥劑學(xué)、藥物配置和藥代動力學(xué)研究的原始報告，特別是那些與藥物治療使用直接相關(guān)的研究。這包括人類藥理學(xué)研究和治療反應(yīng)以及與血漿和組織濃度相關(guān)的藥物及其代謝產(chǎn)物的毒性。對影響藥物臨床反應(yīng)處置的因素的研究，以及基于藥代動力學(xué)原理的藥物劑量方案的設(shè)計和過量治療的研究均被接受。此外，還發(fā)表了關(guān)于體外藥物代謝分析方法和動物模型的論文，只要這些論文有助于上述類型的研究，或者它們與人類藥物的使用有關(guān)。該雜志還發(fā)表評論文章。

英文簡介

The Journal publishes original reports of studies in biopharmaceutics drug disposition and pharmacokinetics especially those which have a direct relation to the therapeutic use of drugs. This includes human pharmacological studies and therapeutic response and toxicity related to plasma and tissue concentrations of drugs and their metabolites. Research on factors affecting the disposition of the clinical response to drugs and on the design of drug dosage regimens and the treatment of overdose based on pharmacokinetic principles are accepted. Papers on analytical methodology in vitro drug metabolism and on animal models are also published provided that either they facilitate the preceding types of investigation or they are related to the use of drugs in man. The Journal also publishes review articles